RANDOMISED MULTICENTRE CLINICAL STUDY

VIRDICT

Vascular Inflammation ReDuction and perivascular fat Imaging by Computed Tomography

VIRDICT investigates whether coronary inflammation measured non-invasively on routine coronary CT angiography can be used to guide preventive treatment and reduce vascular inflammation.

RandomisedOpen-labelMulticentre6-month follow-up
FAI and vascular inflammation concept
STUDY AT A GLANCE

Testing inflammation-guided prevention

The study compares standard-of-care management with CaRi-Heart-based management in adults undergoing CCTA, using change in the Fat Attenuation Index (FAI) as the primary marker of treatment effect on coronary vascular inflammation.

30–80 yearsEligible age range
≥140Participants required for the primary objective
24 weeksPost-randomisation follow-up
3 yearsPlanned trial period
Repeat CCTAAt the final 24-week visit
Research study information

This page is a public summary of the VIRDICT study. Treatment decisions must not be based on this webpage and should follow the approved study protocol and clinical guidance.